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By Michael C. Flickinger, Stephen W. Drew

ISBN-10: 0471138223

ISBN-13: 9780471138228

Encyclopedias composed of: The Encyclopedia of Molecular Biology, the Encyclopedia of Bioprocess know-how: Fermentation, Biocatalysis, and Bioseparation, the Encyclopedia of mobilephone expertise, and the Encyclopedia of moral, felony, and coverage matters in Biotechnology, supplying wide insurance of 4 significant modern issues during this box. DLC: Biochemical engineering--Encyclopedias.

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R. Knowles, Enzyme catalysis: not different, just better, Nature 1991, 350, 121−124. A. Liese and M. V. Filho, Production of fine chemicals using biocatalysis, Curr. Opin. Biotechnol. 1999, 10, 595–603. A. Liese, K. Seelbach, and C. Wandrey, Industrial Biotransformations: A Collection of Processes, VCH, Weinheim, 2000. P. T. Mannisto, Catechol O-methyltransferase: characterization of the protein, its gene, and the preclinical pharmacology of COMT inhibitors, Adv. Pharmacol. 1998, 42, 324–328. J.

Quaranta, R. Liberio, C. Dileo, and I. Tommasi, Enzymic synthesis of 4-hydroxybenzoic acid from phenol and carbon dioxide: the first example of a biotechnological application of a carboxylase enzyme, Tetrahedron 1998, 54, 8841–8846. F. Baneyx, Recombinant protein expression in Escherichia coli, Curr. Opin. Biotechnol. 1999, 10, 411–421. A. S. Bommarius, M. Schwarm, and K. Drauz, Factors for process design towards enantiomerically pure l- and d-amino acids, Chimia 2001, 55, 50–59. P. Carter and J.

While for basic, large-volume chemicals yields of 98 or 99% are absolutely essential, the situation in fine chemicals calls for 90–95% yield, and in the initial stage of production of extreme performance chemicals, such as pharmaceuticals, yields of > 80% are very acceptable; sometimes values down to 50% have to be encountered. Acceptable yields depend on the number of process steps, including product isolation. If all the steps are assumed to fetch 90% yield, the overall yield depends on the number of steps n as in Eq.

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Encyclopedia of Bioprocess Technology by Michael C. Flickinger, Stephen W. Drew

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