By Aliya N. Husain MD
- High caliber colour photomicrographs to focus on key diagnostic features
- Detailed illustrations supplement text
- Special diagnostic strategies particular to small patients
- Chapters geared up by means of organ approach and contain congenital, inflammatory, infectious and neoplastic lesions
- Techniques comprise histochemical and immunohistochemical stains, electron microscopic examinations, and molecular tests
- A robust seek that attracts effects from content material within the e-book, your notes, or even the web
- Cross-linked pages, references, and extra for simple navigation
- Highlighting software for simpler reference of key content material through the text
- Ability to take and proportion notes with buddies and colleagues
- Quick reference tabbing to avoid wasting your favourite content material for destiny use
- A 50 query try out to augment key concepts
- Over one hundred forty bonus figures built-in through the content
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Extra info for Biopsy Interpretation of Pediatric Lesions
Inflammation is usually sparse, but EMH, as seen here, is often prominent (H&E, 400ϫ). (c) 2015 Wolters Kluwer. All Rights Reserved. 7 Typically, portal tracts appear relatively normal in neonatal hepatitis (H&E, 400ϫ). apoptosis, and pseudoglandular or acinar formation. , viral) etiology. The main, and often also the most difficult, differential diagnosis is EHBA. The distinction is, however, important because EHBA requires early surgical correction (portoenterostomy/Kasai procedure).
All Rights Reserved. 24 ——— BIOPSY INTERPRETATION OF PEDIATRIC LESIONS electron microscopic evaluations of intestinal biopsies. Classically, duodenal biopsies show variable villous atrophy, normal to decreased numbers of inflammatory cells in the lamina propria, and normal crypts. 126 In addition, the cytoplasmic inclusions of microvilli in the affected enterocytes can be highlighted by the diastase periodic-acid stain or by CD10 antibody122,126,127 (Fig. 24). 24 A: Ultrastructural examination shows intracytoplasmic inclusions typical of MVID.
All Rights Reserved. 30 A: Numerous foci of crypt epithelial apoptosis (arrows) are seen in this allograft ileum biopsy. The crypt at the lower arrow shows many foci of apoptosis in adjacent epithelial cells. B: Adenovirus inclusions (arrows) are evident in the epithelial cells from this allograft ileum biopsy. REFERENCES 1. Sullivan JS, Sundaram SS. Gastroesophageal reflux. Pediatr Rev. 2012;33:243–253. 2. Maguire A, Sheahan K. Pathology of oesophagitis. Histopathology. 2012;60:864–879. 3. Rodrigues F, Brandão N, Duque V, et al.
Biopsy Interpretation of Pediatric Lesions by Aliya N. Husain MD